Control of Gene Expression in a Bacterial Pathogen

Grant number: 1008055 | Funding period: 2011 - 2013

Completed

Abstract

In this study we will characterise the manner in which genes essential for the virulence of Porphyromonas gingivalis, a bacterium associated with chronic periodontitis, are regulated. This will provide information on how this bacterium causes disease and may offer opportunities for the development of new treatment strategies.

Related publications (2)

The Porphyromonas gingivalis ferric uptake regulator orthologue does not regulate iron homeostasis

C Butler, H Mitchell, S Dashper, E Reynolds

2015-09-01

Porphyromonas gingivalis is a Gram-negative anaerobic bacterium that has an absolute requirement for iron which it transports from..

The Porphyromonas gingivalis ferric uptake regulator orthologue binds hemin and regulates hemin-responsive biofilm development

CA Butler, SG Dashper, L Zhang, CA Seers, HL Mitchell, DV Catmull, MD Glew, JE Heath, Y Tan, HSG Khan, EC Reynolds

2014-11-06

Porphyromonas gingivalis is a Gram-negative pathogen associated with the biofilm-mediated disease chronic periodontitis. P. gingiv..

University of Melbourne Researchers

Eric Reynolds

Stuart Dashper

Lianyi Zhang